Strongyloidiasis in the U.S.

References for healthcare Providers

Compiled by No Morgellons: A Public Awareness Campaign. Last update: 18 Feb 2025. https://nomorgellons.univer.se

Disclaimer: No Morgellons: A Public Awarenes Campaign is NOT a licensed healthcare provider, a government agency, a provider of Continuing Medical Education, or any organization authorized to dispense medical training or advice. The information provided here is freely available to the public and was compiled by a individual with no medical training. No Morgellons: A Public Awareness Campaign disclaims any responsibility regarding actual medical knowledge, advice, or any of the following information.

The following resources offer healthcare providers a comprehensive understanding of strongyloidiasis, from epidemiology and diagnosis to treatment and management strategies. By increasing awareness and improving clinical practices, healthcare providers can play a crucial role in addressing the challenges of this neglected disease that is present and severely under diagnosed in the U.S., in order to achieve better outcomes for patients.

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Maltreatment of Strongyloides infection: case series and worldwide physicians-in-training survey (Boulware et al. 2004)

This study provides insights into the challenges faced by physicians-in-training in diagnosing and treating strongyloidiasis. It highlights the need for improved education and awareness among healthcare professionals, particularly in non-endemic areas, to prevent misdiagnosis and related complications.

A research agenda for helminth diseases of humans: towards control and elimination (Boatin et al. 2012)


A comprehensive review of recent helmintiasis research to identify research gaps and develop future goals for R&D to achieve Health Development goals and outline salient funding needs.

Current pharmacotherapeutic strategies for Strongyloidiasis and the complications in its treatment (Buonfrate et al. 2022)

This article discusses current treatment strategies and the complications involved in managing strongyloidiasis. It highlights the importance of proper dosing and explores alternative treatments, providing a valuable reference for optimizing therapeutic approaches.

The Global Prevalence of Strongyloidiasis: A Systematic Review and Meta-analysis (Buonfrate et al., 2021)

This systematic review and meta-analysis provide valuable insights into the global burden of strongyloidiasis, highlighting the significant underestimation of the disease's prevalence. It underscores the importance of increased surveillance and improved diagnostic techniques to better understand the true impact of this neglected tropical disease.

Severe Strongyloidiasis: A Systematic Review of Case Reports (Buonfrate et al., 2019)

This systematic review of case reports on severe strongyloidiasis, including hyperinfection syndrome and disseminated infections, offers healthcare providers a deeper understanding of the clinical presentation, risk factors, and management of these life-threatening manifestations of the disease.

Strongyloides stercoralis in Texas and the southern United States (Echidna et al. 2020)

This paper discusses the prevalence and implications of Strongyloides stercoralis infections in Texas and the southern United States, highlighting the need for increased awareness and diagnostic efforts in these regions.

Strongyloides stercoralis infection (Greaves et al. 2013)

provides a comprehensive overview of Strongyloides stercoralis infection, including its clinical presentation, diagnosis, treatment options, and the importance of recognizing this neglected tropical disease in affected populations.

Strongyloides Hyperinfection Syndrome and Disseminated Disease with Negative Serology (Hall et al. 2024)

This case study emphasizes the diagnostic challenges of strongyloidiasis, particularly in immunocompromised patients. It underscores the importance of considering alternative diagnostic methods when serology is negative, thus offering practical insights for clinicians.

Ivermectin vs moxidectin for treating Strongyloides stercoralis infection: a systematic review (Henriquez-Camacho et al. 2024)

This systematic review compares the efficacy and safety of ivermectin and moxidectin, providing evidence for clinicians to make informed decisions about treatment options for strongyloidiasis.

Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection (Henriquez-Camacho et al., 2016)

This review article provides guidance on the optimal dosing and duration of ivermectin treatment for strongyloidiasis, emphasizing the importance of ensuring adequate and appropriate treatment to prevent the development of drug resistance and poor clinical outcomes.

Strongyloidiasis in the Immunocompromised Host: A Worm That Leaves No Stone Unturned (Marcos & Terashima, 2007)

This article explores the unique challenges and management considerations for strongyloidiasis in immunocompromised individuals, such as those with HIV/AIDS, organ transplant recipients, and patients receiving immunosuppressive therapies.

A comparative trial of a single-dose ivermectin versus three days of albendazole for treatment of Strongyloides stercoralis and other soil-transmitted helminth infections in children (Marti et al. 1996)

presents a comparative trial evaluating the effectiveness of a single dose of ivermectin against a three-day regimen of albendazole for treating Strongyloides stercoralis and other soil-transmitted helminth infections in children. The study found that ivermectin was effective in treating these infections, demonstrating comparable efficacy to albendazole, while also highlighting the convenience of a single-dose treatment. The results suggest that ivermectin could be a practical alternative for managing these parasitic infections in pediatric populations.

Screening, Prevention, and Treatment for Hyperinfection Syndrome and Disseminated Infections Caused by Strongyloides stercoralis (Mejia & Nutman, 2012)

This article focuses on the critical aspects of managing strongyloidiasis, particularly the prevention and treatment of life-threatening hyperinfection syndrome and disseminated infections. It emphasizes the need for early detection and appropriate treatment to avoid severe complications.

Strongyloidiasis: A Neglected Tropical Disease (Nutman, 2017)

This comprehensive review article provides an in-depth overview of the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of strongyloidiasis. It highlights the importance of increased awareness and improved diagnostic and management strategies among healthcare providers.

Chronic Strongyloidiasis – Don't look and you won't find. (Page & Speare, 2016)

This article discusses the need for improved diagnostic techniques and increased awareness among healthcare providers to better manage and control this parasitic infection.

Strongyloidiasis in the Immunocompromised Host (Ramanathan & Nutman, 2008)

This article focuses on the unique challenges and management strategies for strongyloidiasis in immunocompromised patients, who are at a higher risk of developing severe and disseminated infections. It highlights the need for increased vigilance and proactive screening in this vulnerable population.

Diagnosis of Strongyloides stercoralis Infection (Siddiqui & Berk, 2001)

This article provides a comprehensive overview of the diagnostic challenges and strategies for strongyloidiasis, emphasizing the limitations of commonly used diagnostic methods and the importance of considering alternative testing approaches to improve detection.

Efficacy and safety of single-dose ivermectin versus seven-day high dose albendazole for chronic strongyloidiasis (Suputtamongkol et al. 2011)

compares the efficacy and safety of a single dose of ivermectin to a seven-day course of high-dose albendazole for treating chronic strongyloidiasis. The results indicate that ivermectin is as effective as albendazole in eliminating the infection, with a favorable safety profile. The findings support the use of ivermectin as a viable treatment option for chronic strongyloidiasis.

A 5-year Single Center Review of Strongyloides stercoralis Seropositivity in Cardiac Transplant Candidates in Central Texas (Telchik et al. 2025)

Single health center in Houston retrospective screening of organ transplant patients with tables. Shows there are no epidemiological predictive risk factors, and prevalence of Strongyloides seropositivity is above 11% in the population.

Human Strongyloides stercoralis infection: Review of epidemiology, diagnosis, and management (Yang et al. 2024)

This review article covers the comprehensive aspects of Strongyloides stercoralis infection, from its epidemiology and pathophysiology to the latest diagnostic and treatment strategies. It serves as an essential resource for medical professionals seeking to update their knowledge on this neglected tropical disease.